Unbalanced nutrition and diseases
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Diet, nutrition, and the prevention of chronic diseases. Report of a WHO Study Group.
In the 1950s to '70s, food additives and contaminants were considered important risk factors for cancer and other chronic diseases. Opinion leaders like F. Eichholtz and W. Kollath in Germany and R. Carson and J.J. Delaney in the United States maintained that the exclusion of man-made chemicals from the food supply would decisively contribute to better health. In contrast to these views, world-...
متن کاملA Review on Management of Malnutrition and Deficiency States
Malnutrition is the condition that results from taking an unbalanced diet in which certain nutrients are lacking, in excess (too high an intake), or in the wrong proportions. A number of different nutrition disorders may arise, depending on which nutrients are under or overabundant in the diet. In most of the world, malnutrition is present in the form of undernutrition, which is caused by a die...
متن کاملEarly-Life Nutritional Programming of Health and Disease in The Gambia.
BACKGROUND Exposures during early life are increasingly being recognised as factors that play an important role in the aetiology of chronic non-communicable diseases (NCDs). The "Developmental Origins of Health and Disease" (DOHaD) hypothesis asserts that adverse early-life exposures - most notably unbalanced nutrition - leads to an increased risk for a range of NCDs and that disease risk is hi...
متن کاملThe Journal of Nutrition Symposium: Nutritional Experiences in Early Life as Determinants of the Adult Metabolic Phenotype The Developmental Origins, Mechanisms, and Implications of Metabolic Syndrome
Metabolic syndrome (MetS) represents a combination of cardio-metabolic risk determinants, including central obesity, insulin resistance, glucose intolerance, dyslipidemia, hypertension, hyperinsulinemia, and microalbuminuria. The prevalence of MetS is rapidly increasing worldwide, largely as a consequence of the ongoing obesity epidemic. Environmental factorsduringperiodsearly in development ha...
متن کاملDietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring.
Environmental constraints during early life result in phenotypic changes that can be associated with increased disease risk in later life. This suggests persistent alteration of gene transcription. DNA methylation, which is largely established in utero, provides a causal mechanism by which unbalanced prenatal nutrition results in such altered gene expression. We investigated the effect of unbal...
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